the evaluation of serum level of testosterone and sex hormone- binding globulin in men with type 2 diabetes

The Evaluation of Serum Level of Testosterone and Sex Hormone- Binding Globulin in Men with Type 2 Diabetes

OBJECTIVE: To evaluate the relationship between serum level of testosterone and sex hormone-binding globulin in men with type 2 diabetes. MATERIALS AND METHODS: In this case-control study, forty men aged 40-70 with type 2 diabetes mellitus were randomly selected and compared with 40 non-diabetic men. The two groups were matched for their age and BMI. After complete observation and examination...

Association of sex hormone-binding globulin and free testosterone with mortality in men with type 2 diabetes mellitus.

OBJECTIVE Low circulating testosterone levels have been associated with increased mortality in men. We hypothesized that the prognostic role of testosterone in men with type 2 diabetes mellitus (T2DM) is influenced by its carrier protein sex hormone-binding globulin (SHBG). DESIGN We conducted a prospective cohort study at a tertiary referral centre. METHODS In total, 531 men with T2DM pres...

Sex hormone-binding globulin and risk of type 2 diabetes.

BACKGROUND Circulating sex hormone-binding globulin levels are inversely associated with insulin resistance, but whether these levels can predict the risk of developing type 2 diabetes is uncertain. METHODS We performed a nested case-control study of postmenopausal women in the Women's Health Study who were not using hormone therapy (359 with newly diagnosed type 2 diabetes and 359 controls)....

The Effect of Eight Weeks Pilates Exercise on Testosterone and Sex Hormone Biding Globulin (SHBG) in Women with Type 2 Diabetes

The association between sex hormone-binding globulin and type 2 diabetes in Nigerian men

BACKGROUND Epidemiological studies have shown that sex hormone-binding globulin (SHBG) has a role in glucose homeostasis in both men and women. However, a prospective study on Japanese-American subjects concluded that SHBG was not a significant risk factor in either men or women, suggesting ethnic differences. We were not aware of any evaluation of SHBG in subjects of African ancestry. OBJECT...

Testosterone and sex hormone-binding globulin predict the metabolic syndrome and diabetes in middle-aged men.

OBJECTIVE In men, hypoandrogenism is associated with features of the metabolic syndrome, but the role of sex hormones in the pathogenesis of the metabolic syndrome and diabetes is not well understood. We assessed the association of low levels of testosterone and sex hormone-binding globulin (SHBG) with the development of the metabolic syndrome and diabetes in men. RESEARCH DESIGN AND METHODS ...